The Role of Advanced Imaging Techniques in Predicting Cardiovascular Outcomes in Asymptomatic Individuals: A Systematic Review and Meta-analysis

Background: Global trends in cardiovascular death have declined and survival rates have decreased over the last 30 years as a result of advancements in medical and interventional therapy.

Objectives: This systematic evaluation and meta-assessment aim to evaluate the predictive efficacy of superior imaging techniques, in particular, CCTA, in asymptomatic people, aiming to elucidate their potential advantages and disadvantages for screening purposes and offer insights into their suitability for risk stratification and control on this populace, informing future scientific recommendations and practices in cardiovascular screening.

Methods: PubMed and Cochrane Library were searched thoroughly for literature search. Ten articles were extracted to be included in this study.

Results: A total of ten studies were included in this systematic review and meta-analysis. All of the included studies were cohorts either retrospective or prospective cohorts. Meta-analysis was performed for two variables that are Cardiovascular Mortality and MACE. Cardiovascular mortality was shown to be improved with the use of Coronary Computed Tomographic Angiography (CCTA). Only one study reported the quantitative effect of CCTA on MACE.

Conclusion: To conclude, our systematic overview and meta-analysis highlight the tremendous position of CCTA in predicting cardiovascular consequences in asymptomatic individuals, suggesting its potential as a precious danger assessment tool for detecting CAD and enhancing cardiovascular mortality prediction, though similar research is wanted to verify its definitive role in medical practice.