Saha, Subbroto Kumar and Haque, Md. Ezazul and Islam, Dipa and Rahman, Md. Matiar and Islam, Md. Rezuanul and Parvin, Anzana and Rahman, Shahedur (2012) Comparative study between the effect of Momordica charantia (wild and hybrid variety) on hypoglycemic and hypolipidemic activity of alloxan induced type 2 diabetic long-evans rats. Journal of Diabetes Mellitus, 02 (01). pp. 131-137. ISSN 2160-5831
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Abstract
This study was undertaken to evaluate the hypoglycemic and hypolipidemic effect of Momordica charantia (wild and hybrid variety) powder on alloxan induced type 2 diabetic male Long-Evans rats. Oral feeding of the M. charantia powder slightly decreased serum total cholesterol, triglyceride levels and LDL-cholesterol compared with wild, hybrid and standard drug. M. charantia wild variety showed more significant (p < 0.05, 0.01, 0.001) effect on blood glucose level when compared with hybrid variety and standard drug (glibenclamide, 5 mg/kg). At the same time rats’ serum insulin level markedly increased, wild variety showed more significant (p < 0.05, 0.01, 0.001) than glibenclamide control group and hybrid group. But M. charantia did not show any significant effect on HDL-cholesterol and liver glycogen. Thus, results of the study prove that the wild variety of M. charantia fruit have potent antidiabetic and antilipidemic property.
Item Type: | Article |
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Subjects: | Open Library Press > Medical Science |
Depositing User: | Unnamed user with email support@openlibrarypress.com |
Date Deposited: | 13 Mar 2023 09:18 |
Last Modified: | 04 Sep 2024 03:49 |
URI: | http://info.euro-archives.com/id/eprint/760 |